Regulación de la EMT-MET y la quimioresistencia por la Lc3Cer-sintasa B3GNT5

Laura E Clark1, Katherine Hylton Rorie1, Amanda J G Dickinson1

  • 1Department of Biology, Virginia Commonwealth University, Richmond, VA, 23284, USA.

BMC cancer
|August 23, 2025
PubMed
Resumen

El gen B3GNT5 regula los glucosfingolipidos (GSL) cruciales para el cáncer maligno. Su alteración en los cánceres se correlaciona con malos resultados, lo que sugiere que B3GNT5 es un objetivo terapéutico potencial.

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