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Conocimientos sobre la interacción molecular entre el polímero y la loratadina poco soluble en agua en la dispersión

Jincao Tang1, Huai He1, Chi Ma1

  • 1Chongqing Key Laboratory of Digitalization of Pharmaceutical Processes, College of Chemistry and Chemical Engineering, Chongqing University of Science and Technology, Chongqing 401331, China.

Chemical & pharmaceutical bulletin
|August 24, 2025
PubMed
Resumen

Las simulaciones de dinámica molecular predicen la miscibilidad de la loratadina (LOR) con polímeros, mejorando la solubilidad del fármaco. Este método acelera el desarrollo de dispersiones sólidas (SD) para medicamentos poco solubles.

Palabras clave:
Interaccióny la loratadinamezclabilidadDinámica molecularel polímerodispersión sólida

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