Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Neurochemical Transmission: Sites of Drug Action01:26

Neurochemical Transmission: Sites of Drug Action

2.6K
Neurochemical transmission, the conduction of electrical impulses between neurons mediated by neurotransmitters, plays a vital role in various physiological processes. Autonomic drugs exert their effects by modulating neurotransmission within the autonomic nervous system. For instance, drugs such as hemicholinium block the precursor uptake necessary for synthesizing acetylcholine, an essential autonomic neurotransmitter. Following synthesis, neurotransmitters are stored in vesicles. Metyrosine...
2.6K
Adrenergic Neurons: Neurotransmission01:27

Adrenergic Neurons: Neurotransmission

4.1K
Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or adrenergic neurons. Noradrenaline, dopamine, adrenaline, or epinephrine are collectively called "catecholamines" as they contain a catechol moiety and an amine side chain. The five stages of neurotransmitter release involve their synthesis, storage, release, reuptake and metabolism.
Synthesis: Catecholamine synthesis requires tyrosine, which...
4.1K
Drugs Affecting Neurotransmitter Release or Uptake01:21

Drugs Affecting Neurotransmitter Release or Uptake

1.2K
Certain drugs can affect how neurotransmitters called catecholamines, are released or taken back up in the adrenergic neuron. They can have different effects on the body's sympathetic transmission. Reserpine, a natural compound found in the Rauwolfia shrub, blocks a transporter called vesicular monoamine transporter (VMAT), which leads to a buildup of catecholamines in the cell and reduces sympathetic transmission. Another drug called guanethidine works in multiple ways, including blocking...
1.2K
Diencephalon: Hypothalamus and Coordination01:23

Diencephalon: Hypothalamus and Coordination

2.2K
The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
2.2K
Diencephalon: Anatomical Regions01:30

Diencephalon: Anatomical Regions

2.9K
The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the...
2.9K
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

400
Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
400

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Quantitative and Phylogenetic Analyses of Immature Neurons in Cortical Layer II and Amygdala of Macaque Monkeys.

Cells·2026
Same author

Comparative analysis of the cellular landscape in mammalian striatum.

Nature communications·2026
Same author

Homologous specialization of arcuate fasciculus ventrolateral frontal connectivity in marmosets and humans.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Morphological and anatomical variations in subcortical anatomy between humans and chimpanzees associated with heritability patterns related to human behavioral traits.

Communications biology·2026
Same author

Mixed Signals and Interspecies Variation in the Plasticity of Adult Mammal Brains.

Cells·2026
Same author

Hominoid-specific calretinin-immunopositivity of the optic radiation (geniculocalcarine tract).

Anatomical record (Hoboken, N.J. : 2007)·2025

Video Experimental Relacionado

Updated: Sep 10, 2025

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

25.9K

La distribución de la inervación del transportador serotoninérgico en el núcleo accumbens y el pálido ventral está

Heather N Smith1,2, Danielle N Jones1,2, Emily L Munger1

  • 1Department of Anthropology and School of Biomedical Sciences, Kent State University, Kent, Ohio, USA.

The Journal of comparative neurology
|August 25, 2025
PubMed
Resumen

La inervación serotoninérgica en el núcleo accumbens y el pálido ventral se conserva en todas las especies de primates. Esto contrasta con las diferencias específicas de las especies que se encuentran en otras regiones del cerebro y en los neurotransmisores.

Palabras clave:
los ganglios basalesLa evolución del hombreCamino de la recompensacomportamiento socialEstriado

Más Videos Relacionados

Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology
07:25

Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology

Published on: March 27, 2018

8.7K
Imaging Serotonergic Fibers in the Mouse Spinal Cord Using the CLARITY/CUBIC Technique
09:54

Imaging Serotonergic Fibers in the Mouse Spinal Cord Using the CLARITY/CUBIC Technique

Published on: February 26, 2016

10.6K

Videos de Experimentos Relacionados

Last Updated: Sep 10, 2025

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
09:54

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area

Published on: August 10, 2012

25.9K
Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology
07:25

Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology

Published on: March 27, 2018

8.7K
Imaging Serotonergic Fibers in the Mouse Spinal Cord Using the CLARITY/CUBIC Technique
09:54

Imaging Serotonergic Fibers in the Mouse Spinal Cord Using the CLARITY/CUBIC Technique

Published on: February 26, 2016

10.6K

Área de la Ciencia:

  • La neurociencia
  • Anatomía comparada
  • Comportamiento de los primates

Sus antecedentes:

  • El núcleo accumbens (NAcc) y el pálido ventral (VP) son cruciales para el procesamiento de la recompensa, la motivación social y el apego.
  • Las especies de primates exhiben diversos comportamientos sociales, influenciados por la neuromodulación dentro de la vía de recompensa.
  • Las diferencias en los neurotransmisores pueden ser la base de los patrones de comportamiento social específicos de cada especie.

Objetivo del estudio:

  • Investigar los patrones de inervación serotoninérgica en el NAcc y el VP en 13 especies de primates.
  • Para comparar la densidad de inervación serotoninérgica en estas regiones de la vía de recompensa entre humanos, monos y monos.

Principales métodos:

  • Cuantificación estereológica de la densidad de longitud del axón del transportador-inmunorreactivo de la serotonina (SERT-ir).
  • Análisis de muestras de tejido NAcc y VP de 13 especies de primates.
  • Análisis comparativo de los patrones de inervación entre los taxones de primates.

Principales resultados:

  • Se encontró que la densidad de inervación serotoninérgica en el NAcc y el VP era altamente conservada en todas las especies de primates estudiadas.
  • Esta conservación contrasta con los hallazgos anteriores de variaciones específicas de especies en otras áreas del cerebro y sistemas de neurotransmisores.
  • Destaca un patrón mosaico de la evolución neuroquímica en el cerebro de los primates.

Conclusiones:

  • La inervación serotoninérgica del NAcc y VP representa una característica conservada del sistema de recompensa de los primates.
  • Las adaptaciones específicas de la especie en el comportamiento social pueden ser impulsadas por la inervación diferencial en otras regiones del cerebro o por otros sistemas de neurotransmisores.
  • Los hallazgos contribuyen a comprender la evolución del comportamiento social en los primates.