Video Experimental Relacionado

Updated: Sep 10, 2025

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology
09:12

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Published on: May 3, 2021

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Las características espaciales y electrónicas que impulsan la selectividad de SGLT1/2: un estudio combinado de

Bingkun Chen1,2,3, Baichun Hu1,2,4, Yuxiang Zong1,2,4

  • 1Key Laboratory of Intelligent Drug Design and New Drug Discovery of Liaoning Province, Shenyang Pharmaceutical University, Shenyang 110016, China. jiaxian206@163.com.

Physical chemistry chemical physics : PCCP
|August 26, 2025
PubMed
Resumen

El diseño de inhibidores selectivos del cotransportador de sodio y glucosa (SGLT) para la diabetes es un desafío debido a la similitud de SGLT1/ 2. La complementariedad espacial en los bolsillos de unión es clave para la selectividad del inhibidor, guiando el diseño de fármacos futuros.

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