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Chinmayee Panda¹, Ralph Kruse², Kaya Williams¹

¹Nutrition Innovation Center, Standard Process Inc., Kannapolis, NC, United States.

Frontiers in nutrition

|August 27, 2025

Resumen

Los suplementos de alimentos integrales ayudan a las transiciones saludables de la dieta al reducir el estrés oxidativo y mejorar la salud intestinal. Este estudio muestra beneficios para la resiliencia metabólica, la función renal y el bienestar psicológico.

Área de la Ciencia:

Ciencias de la nutrición
Salud metabólica
Investigación del microbioma

Sus antecedentes:

Mantener una dieta saludable es crucial para los beneficios metabólicos a largo plazo, pero a menudo es un desafío.
Los suplementos a base de alimentos integrales pueden mejorar la resistencia metabólica durante los cambios en la dieta.
Las intervenciones dietéticas requieren apoyo para optimizar la desintoxicación, el estrés oxidativo y la microbiota intestinal.

Objetivo del estudio:

Evaluar un programa de purificación de 21 días con alimentos vegetales y suplementos alimenticios.
Evaluar el impacto en la desintoxicación metabólica, el estrés oxidativo y la composición de la microbiota intestinal.
Para determinar los efectos sobre la función renal y los marcadores de estrés psicológico.

Principales métodos:

Diseño de estudio cruzado aleatorio y controlado.
Los participantes consumieron una dieta a base de plantas, con proteínas magras añadidas más tarde.
La intervención incluyó suplementos ricos en polifenoles, glucosinolatos y fibras prebióticas.

Principales resultados:

Se observó una reducción del 9% en el estrés oxidativo asociado a las especies reactivas de oxígeno (ROS).
El aumento de la creatinina urinaria indicó una mayor eficiencia de filtración renal.
Se observaron reducciones significativas en el estrés y la ansiedad autoinformados.
El análisis de la microbiota intestinal mostró una disminución de Proteobacteria y un aumento de bacterias beneficiosas como Ruminococcus gnavus.

Conclusiones:

La suplementación de alimentos integrales apoya las transiciones dietéticas al reducir el estrés oxidativo.
La intervención tiene un impacto positivo en la función renal y alivia el estrés psicológico.
La modulación de la composición de la microbiota intestinal sugiere una mejora de la integridad de la barrera intestinal y la producción de butirato.

Palabras clave:

botánico Desintoxicación La microbiota intestinal un estilo de vida más saludable salud metabólica El estrés oxidativo dieta a base de vegetales Alimentos enteros

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