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Updated: Sep 10, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Síntesis de nucleósidos carbocíclicos de ciclopropilo a través de la ciclopropanación reductora mediada por P

Ke-Xin Huang1, Ya-Xuan Yu1, Zhao-Yang Chen1

  • 1School of Biological and Chemical Engineering, Institute of Biology and Pharmaceutical Research, Nanyang Institute of Technology, Nanyang, Henan 473000, China.

The Journal of organic chemistry
|August 27, 2025
PubMed
Resumen

Se ha desarrollado un nuevo método para sintetizar nucleósidos carbocíclicos de ciclopropilo utilizando ciclopropanación reductora mediada por fósforo (III) tris (dimetilamida). Este eficiente protocolo libre de metales ofrece una ruta práctica para estos importantes compuestos.

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