Video Experimental Relacionado

Updated: Sep 10, 2025

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
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Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

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Decodificación de ADGRE5: Cómo la escisión proteolítica y las fuerzas mecánicas liberan señales celulares

Ana L Moreno-Salinas1, Arturo Mancini2, Samya Aouad2,3

  • 1Department of Pharmacology-Physiology, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

Cells
|August 27, 2025
PubMed
Resumen

La señalización del receptor acoplado a la proteína G ADGRE5 (CD97) es compleja. Este estudio revela nuevas vías de activación, incluidos los mecanismos independientes de la escisión GPS y la estimulación mecánica, cruciales para el desarrollo de medicamentos oncológicos.

Palabras clave:
ADGRE5 (en inglés)El proyecto BRETEl CD55aGPCRs (en inglés)señalización sesgadaestimulación mecánica

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