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Protocolo para investigar la modulación de la memoria de trabajo del procesamiento de señales visuales en la corteza

Majid Roshanaei¹, Mohammad Reza Daliri¹, Zahra Bahmani²

¹Neuroscience & Neuroengineering Research Lab, Biomedical Engineering Department, School of Electrical Engineering, Iran University of Science and Technology (IUST), Narmak, Tehran 16846-13114, Iran.

|August 27, 2025

Resumen

Este estudio describe un protocolo para examinar cómo la memoria de trabajo influye en el procesamiento visual en el cerebro. Detalla los métodos para registrar la actividad neuronal durante una tarea de memoria de trabajo espacial en monos.

Área de la Ciencia:

La neurociencia
La neurociencia cognitiva
Investigación sobre los primates

Sus antecedentes:

La corteza extrastriada es crucial para el procesamiento de señales visuales.
Comprender la influencia de los estados cognitivos como la memoria de trabajo en la actividad neuronal es vital.

Objetivo del estudio:

Presentar un protocolo detallado para investigar el impacto de la memoria de trabajo en el procesamiento de señales visuales.
Establecer una metodología para el registro y análisis de datos neuronales en respuesta a estímulos visuales bajo carga de memoria de trabajo.

Principales métodos:

Una tarea de memoria de trabajo espacial fue diseñada para monos.
Los potenciales de campo locales (LFP) y la actividad de picos se registraron en las neuronas temporales medias (MT).
Se realizó un preprocesamiento y análisis de los datos de LFP utilizando coherencia entre ensayos (ITC) para determinar los tiempos de llegada de la señal visual.

Principales resultados:

El protocolo permite la medición de los tiempos de llegada de la señal visual en la corteza extrastriada.
Permite la investigación de cómo la memoria de trabajo modula las respuestas neuronales.

Conclusiones:

Este protocolo proporciona un marco para estudiar la interacción entre la memoria de trabajo y la percepción visual.
Facilita la investigación futura en los mecanismos neuronales que subyacen al control cognitivo del procesamiento sensorial.

Palabras clave:

Comportamiento La neurociencia cognitiva La neurociencia

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