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Síndrome de Cogan atípico con manifestaciones auditivas y oculares tardías
Iden Amiri1, Johnson Hoang1, Khalid Aldaas1
1Ophthalmology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
BMJ case reports
|August 27, 2025
Resumen
El síndrome de Cogan atípico, una rara condición inflamatoria de los ojos y los oídos, fue diagnosticado en una mujer joven con enfermedad sistémica. El tratamiento temprano con corticosteroides mejoró rápidamente su visión y audición.
Área de la Ciencia:
- Oftalmología
- Reumatología
- Nefrología
Sus antecedentes:
- El síndrome de Cogan es un trastorno autoinmune raro que afecta a los ojos y los oídos.
- Las presentaciones atípicas pueden plantear desafíos de diagnóstico, especialmente con la participación sistémica.
Objetivo del estudio:
- Para reportar un caso de síndrome de Cogan atípico en una mujer joven con comorbilidades sistémicas significativas.
- Para poner de relieve las dificultades de diagnóstico y la importancia de un tratamiento rápido.
Principales métodos:
- Informe de caso detallando la presentación clínica, el historial médico, el diagnóstico y la respuesta al tratamiento.
- Diagnóstico de exclusión basado en hallazgos clínicos, historial y respuesta al tratamiento.
Principales resultados:
- El paciente presentaba proposis, dolor ocular, visión borrosa y presión intraocular elevada.
- Los corticosteroides sistémicos condujeron a una rápida mejora en la agudeza visual y la resolución de los síntomas.
- Las pruebas infecciosas y autoinmunes fueron negativas, apoyando un diagnóstico atípico.
Conclusiones:
- El síndrome de Cogan atípico requiere un alto índice de sospecha, especialmente en pacientes con enfermedad sistémica y aparición tardía.
- El reconocimiento inmediato y el inicio de la terapia con corticosteroides son cruciales para prevenir la pérdida irreversible de la visión y la audición.
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