Video Experimental Relacionado

Updated: Sep 10, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

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La deficiencia de CDK5RAP3 está asociada con la inflamación hepática y el aumento de la expresión de los componentes

Xinjin Chen1, Yaqi Huang1, Yilin Wu1

  • 1College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.

Biomedicines
|August 28, 2025
PubMed
Resumen

La deficiencia de CDK5RAP3 causa daño hepático e inflamación en ratones mediante la activación de la vía inflamatoria del NLRP3, lo que lleva a la piroptosis y la apoptosis. Esta proteína es crucial para mantener la homeostasis del hígado.

Palabras clave:
El CDK5RAP3El inflamatorio NLRP3La apoptosisInflamación hepáticalesión hepáticaLa piróptosis

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