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Características clínicas patológicas y endoscópicas del linfoma alimentario difuso en perros

Florian Bedel¹, Adeline Betting¹, Maud Girod¹

¹Department of Internal Medicine, Centre Hospitalier Veterinaire OnlyVet, 69800 Saint-Priest, France.

Veterinary sciences

|August 28, 2025

Resumen

El linfoma alimentario difuso (LA) en perros es poco conocido. La aparición de un " piedrecillo " en el duodeno en perros con AL indica un peor pronóstico, con una menor cantidad de albúmina y tiempos de supervivencia más cortos.

Área de la Ciencia:

Medicina Veterinaria
Gastroenterología
En el campo de la oncología

Sus antecedentes:

El linfoma alimentario difuso (LA) en perros es una enfermedad poco caracterizada.
La falta de criterios de diagnóstico bien definidos dificulta una gestión eficaz.
Este estudio tiene como objetivo caracterizar la AL en perros.

Objetivo del estudio:

Evaluar las características clínicas, endoscópicas, histopatológicas e inmunohistoquímicas de la AL difusa canina.
Identificar posibles marcadores de diagnóstico y indicadores de pronóstico.
Correlacionar los hallazgos endoscópicos con los resultados clínicos.

Principales métodos:

Evaluación retrospectiva de 18 perros diagnosticados con AL difusa (2017-2024).
Criterios de inclusión: ecografía abdominal, endoscopia gastrointestinal con biopsias, histopatología y inmunohistoquímica.
Criterios de exclusión: perros con masas intestinales.

Principales resultados:

El duodeno fue el sitio afectado con mayor frecuencia.
En el 53% de los perros se observó una apariencia endoscópica de " pedernal ".
Los perros con apariencia de " piedra de acantilado " tenían menor cantidad de albúmina, puntuaciones CCECAI más altas y tiempos de supervivencia significativamente más cortos (p=0,02).

Conclusiones:

La aparición de la mucosa duodenal de " piedras de acantilado " está asociada con un perfil clínico y biológico más severo en la AL difusa canina.
Se necesita más investigación para aclarar el valor diagnóstico de estas lesiones endoscópicas.
Este hallazgo puede ayudar en la identificación temprana y la estratificación del riesgo de perros con AL.

Palabras clave:

endoscopia de las vías urinarias por vía gastrointestinal el linfoma

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