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Dinámica de la circulación global y sus determinantes del virus del dengue: un estudio de la evolución de la red y el
Haoyu Long1,2, Jinfeng Zeng1,2,3, Yilin Chen1,2,4
1School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou 510275, China.
Viruses
|August 28, 2025
Resumen
Comprender la circulación del virus del dengue es clave para su control. Este estudio revela las principales fuentes, destinos y factores climáticos / aéreos que impulsan el dengue
Área de la Ciencia:
- Epidemiología
- Virología
- Ciencia de las redes
Sus antecedentes:
- El dengue es un problema de salud mundial cada vez mayor.
- La prevención y el control precisos requieren comprender la dinámica de la circulación del virus del dengue.
Objetivo del estudio:
- Para explorar la dinámica de circulación global de los cuatro serotipos del virus del dengue.
- Identificar los factores clave que influyen en la propagación del dengue.
Principales métodos:
- Utilizó secuencias genéticas y un método basado en redes.
- Se han definido nuevos indicadores de circulación: intensidad local, centralidad intermedia, frecuencia de caída, tiempo de persistencia.
- Las funciones de circulación propuestas: origen, centro y destino.
- Se emplearon modelos de aprendizaje automático para evaluar los determinantes.
Principales resultados:
- Regiones de origen clave identificadas (por ejemplo, Tailandia, Indonesia, Vietnam, Venezuela, Colombia) y regiones de destino (naciones insulares).
- Se observaron aumentos significativos en las regiones con roles de circulación y persistencia del serotipo 1 del virus del dengue (DENV-1) durante décadas.
- Determinado que el clima y los viajes aéreos son factores significativos que influyen en la circulación y persistencia del dengue.
Conclusiones:
- Los roles y determinantes de circulación identificados ofrecen nuevas perspectivas sobre la dinámica mundial del dengue.
- Los hallazgos son beneficiosos para las estrategias de prevención y control del dengue.
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