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Características tratables en la tos crónica: una evaluación prospectiva para predecir la persistencia de la tos
Yeonhee Kim1, Seung-Eun Lee2,3, Eun-Jung Jo2
1Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
ERJ open research
|August 28, 2025
Resumen
Los síntomas de hipersensibilidad a la tos y la edad avanzada están relacionados con la tos crónica persistente. Este estudio sugiere que estos factores afectan los resultados a largo plazo, orientando la investigación futura en el manejo de la tos crónica.
Área de la Ciencia:
- Pulmonología
- Medicina Clínica
- Investigación de las vías respiratorias
Sus antecedentes:
- La utilidad clínica de los rasgos tratables para el tratamiento de la tos crónica requiere más evidencia.
- Este estudio examina el vínculo entre las características iniciales del paciente y la persistencia de la tos crónica.
Objetivo del estudio:
- Investigar la asociación entre los rasgos tratables y la persistencia de la tos crónica.
- Identificar los factores que predicen los resultados a largo plazo de la tos en pacientes con tos crónica.
Principales métodos:
- Análisis prospectivo del registro de 426 pacientes con tos crónica.
- Evaluación de 11 rasgos potencialmente tratables en la línea de base.
- Definición de la persistencia de la tos como una puntuación de la escala analógica visual (VAS) >20 en el seguimiento.
Principales resultados:
- El 50,5% de los pacientes experimentó tos persistente después de una mediana de seguimiento de 12 meses.
- Los síntomas de hipersensibilidad a la tos (41,8%) fueron el rasgo más frecuente asociado con la persistencia.
- El análisis multivariado reveló síntomas de hipersensibilidad a la tos (aOR 1,78) y edad avanzada (aOR 2,07) como predictores independientes de la tos persistente.
Conclusiones:
- Los síntomas de hipersensibilidad a la tos están significativamente asociados con los resultados a largo plazo de la tos crónica.
- La edad avanzada también es un factor independiente asociado con la tos persistente.
- Se necesita más investigación para validar los rasgos tratables y comprender los factores que influyen en la persistencia de la tos crónica.
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