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Updated: Sep 9, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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Genes establecidos de predisposición al cáncer en diagnósticos de cáncer único y múltiple

Jeffrey W Shevach1, Jianfeng Xu2, Nathan Snyder1

  • 1Department of Medicine and the Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina.

JAMA oncology
|August 28, 2025
PubMed
Resumen

Las variantes patógenas raras (RPV) en 16 genes de predisposición al cáncer están relacionadas con el aumento de las probabilidades de diagnósticos de cáncer único y múltiple en un estudio de gran población. Las pruebas de panel multigénico pueden ser beneficiosas para las personas con estas variantes.

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