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Exploración del crecimiento excesivo de bacterias en el intestino delgado en trastornos funcionales
Bhaswati C Acharyya1,2, Meghdeep Mukhopadhyay1
1Department of Pediatric Gastroenterology and Hepatology, Institute of Child Health, Kolkata 700017, West Bengal, India.
World journal of clinical pediatrics
|August 29, 2025
Resumen
El crecimiento excesivo de bacterias en el intestino delgado (SIBO) es común en niños con síntomas gastrointestinales superiores inexplicables. Se recomienda investigar la SIBO en estos pacientes pediátricos, incluso con hallazgos endoscópicos normales.
Área de la Ciencia:
- Gastroenterología pediátrica
- Investigación del microbioma
- Precisión del diagnóstico
Sus antecedentes:
- El crecimiento excesivo de bacterias del intestino delgado (SIBO) se sospecha con frecuencia en trastornos gastrointestinales funcionales.
- Los niños con síntomas gastrointestinales superiores a menudo no se prueban para SIBO.
Objetivo del estudio:
- Determinar la prevalencia de SIBO en niños con síntomas funcionales de la parte superior del aparato digestivo.
- Para comparar el estado de SIBO en niños con y sin lesiones endoscópicas.
Principales métodos:
- 129 niños (6-18 años) con síntomas gastrointestinales superiores fueron sometidos a endoscopia antes de tomar inhibidores de la bomba de protones (IPP).
- Los casos tenían endoscopia normal; los controles tenían lesiones endoscópicas.
- Las pruebas de aliento de glucosa-hidrógeno diagnosticaron SIBO en ambos grupos.
Principales resultados:
- Se diagnosticó SIBO en el 59% de los niños con endoscopia normal (casos) frente al 21% con lesiones (controles).
- La relación de probabilidades para SIBO en los casos fue de 5,38, lo que indica una asociación significativa.
- Las náuseas, la halitosis y la plenitud epigástrica predijeron SIBO en niños.
Conclusiones:
- La investigación SIBO es valiosa para los niños con síntomas gastrointestinales superiores inexplicables por endoscopia.
- El diagnóstico y el tratamiento tempranos de SIBO pueden mejorar los resultados de salud gastrointestinal pediátrica.
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