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Updated: Sep 9, 2025

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Papel de los receptores de orexina en el procesamiento pruriceptivo inducido por histamina y cloroquina

Anna Kanemaru-Kawazoe1, Hideki Funahashi1, Yoichiro Kogoh1

  • 1Department of Psychiatry, Division of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki city, Miyazaki 889-1692, Japan.

Neuroscience research
|August 29, 2025
PubMed
Resumen

Orexin A (OX-A) reduce efectivamente las respuestas de picazón a la histamina y la cloroquina (CQ) al actuar sobre los receptores de orexina. Esto sugiere que los péptidos de orexina juegan un papel clave en la modulación de las vías de señalización de la picazón.

Palabras clave:
C-FosEl ratónLos receptores OX1Los receptores OX2La orexina ALa orexina BComportamiento de rascado

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