Video Experimental Relacionado

Updated: Sep 9, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice

Published on: June 22, 2016

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Lpar5 regula la respuesta de las células T CD8 a la infección persistente del virus al alterar la programación de

Marc A D'Antonio1, Brian C Ware1,2, James E DiLisio1

  • 1Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States.

Journal of immunology (Baltimore, Md. : 1950)
|August 29, 2025
PubMed
Resumen

La señalización del receptor del ácido lisofosfatídico 5 (LPAR5) regula el agotamiento de las células T CD8. El bloqueo de LPAR5 en ratones mejora la supervivencia y la función de las células T CD8 durante las infecciones virales crónicas, mejorando la inmunidad antitumoral.

Palabras clave:
Células T CD8El LCMVAcceso a la informaciónEl LPAR5Agotamiento de las células T

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