Video Experimental Relacionado

Updated: Sep 9, 2025

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
09:29

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

Published on: May 4, 2016

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Los filamentos de actina peri-mitocondriales inhiben el ensamblaje de Parkin al interrumpir los contactos

Tak Shun Fung1, Amrapali Ghosh2, Maite R Zavala2

  • 1Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

EMBO reports
|August 29, 2025
PubMed
Resumen

La actina inducida por daño agudo (ADA) retrasa la mitofagia después del daño mitocondrial. La inhibición de la ADA acelera el reclutamiento de Parkin y restaura la mitofagia durante el daño crónico al interrumpir los contactos ER-mitocondria.

Palabras clave:
Actina y sus derivadosComplejo Arp2/3En la sala de emergenciasLC3 y LC3El estacionamiento.

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