Video Experimental Relacionado
Updated: May 7, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
20.5K
Crioterapia adaptativa guiada por imágenes para el tratamiento del cáncer de próstata
Eva Beek1,2, Nobuhiko Hata3, Kemal Tuncali4
1Department of Radiology, Brigham & Women's Hospital, Harvard Medical School, 75 Francis St., Boston, 02115, MA, USA. e.x.beek@student.tue.nl.
Annals of biomedical engineering
|August 29, 2025
Resumen
La crioterapia adaptativa guiada por imágenes (ImAC) optimiza el tratamiento del cáncer de próstata al mejorar la precisión de la colocación de la aguja. Este nuevo enfoque puede reducir la experiencia necesaria para una crioablación focal efectiva.
Área de la Ciencia:
- Urología
- Imágenes médicas
- En el campo de la oncología
Sus antecedentes:
- La crioablación focal es un tratamiento para el cáncer de próstata con efectos secundarios reducidos.
- La experiencia del médico es crucial para controlar la desviación de la aguja durante la crioablación.
Objetivo del estudio:
- Desarrollar y evaluar la crioterapia adaptativa guiada por imágenes (ImAC) para la crioablación prostática guiada por resonancia magnética.
- Determinar si ImAC puede optimizar la colocación de la aguja y reducir los requisitos de experiencia médica.
Principales métodos:
- ImAC fue diseñado para calcular la colocación óptima de la aguja teniendo en cuenta la desviación de la aguja y la formación de bolas de hielo.
- El rendimiento del sistema se evaluó a través de simulaciones de 21 inserciones de agujas.
Principales resultados:
- ImAC logró un margen mínimo de ablación mediano mayor (5,0 mm) en comparación con un médico experimentado (3,4 mm).
- Los ajustes de la colocación de la aguja fueron similares entre el ImAC y el médico (±7,5 mm).
Conclusiones:
- ImAC demuestra potencial para optimizar la colocación de la aguja en la crioablación de próstata.
- Esta estrategia adaptativa puede disminuir la curva de aprendizaje para procedimientos efectivos de crioablación.
Videos de Conceptos Relacionados
02:18Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
02:56Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
02:57Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
01:27Tumor Immunotherapy
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.