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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

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Video Experimental Relacionado

Updated: Jun 9, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
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[Disfunción prefrontal y negatividad de desajuste en la depresión adolescente: un estudio multimodal fNIRS-ERP]

Hongyi Sun1, Lin Zhang2, Jing Li3

  • 1Neurobiological Laboratory, West China Hospital of Sichuan University, Chengdu 610041, P. R. China.

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
|August 31, 2025
PubMed
Resumen
Este resumen es generado por máquina.

La depresión adolescente muestra actividad cerebral alterada, con negatividad de desajuste prolongada (MMN) y oxigenación reducida de la corteza frontal. Estos hallazgos sugieren un deterioro del procesamiento sensorial y la hipofunción prefrontal en los jóvenes deprimidos, lo que ayuda al desarrollo temprano de biomarcadores.

Área de la Ciencia:

  • La neurociencia
  • Psicología clínica
  • Los biomarcadores
Palabras clave:
AdolescentesLa depresiónPotenciales relacionados con el eventoEspectroscopia funcional del infrarrojo cercanoNegatividad de desajuste

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