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Conocimientos avanzados sobre la psoriasis: desde la patogénesis hasta las terapias actuales y emergentes
Maria Beatriz S Gonçalves1, Mariana Fonseca1, Filipa Mascarenhas-Melo2
1Laboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.
International immunopharmacology
|September 1, 2025
Resumen
La psoriasis en placas, una enfermedad crónica de la piel, implica factores genéticos y ambientales. Los tratamientos actuales son limitados, lo que impulsa la investigación de nuevas terapias como los biológicos y las formulaciones tópicas mejoradas para una mejor eficacia.
Área de la Ciencia:
- Dermatología
- Inmunología
- Farmacología
Sus antecedentes:
- La psoriasis en placas es una enfermedad cutánea común, crónica y mediada por el sistema inmunológico.
- La patogénesis implica predisposición genética y factores ambientales, que afectan la calidad de vida.
Objetivo del estudio:
- Revisar las innovaciones recientes en el tratamiento de la psoriasis.
- Resaltar los nuevos medicamentos biológicos, los biosimilares y los avances en la formulación tópica.
Principales métodos:
- Revisión de la literatura sobre las terapias actuales y emergentes para la psoriasis.
- Análisis de la eficacia y los inconvenientes del tratamiento.
Principales resultados:
- Nuevos medicamentos biológicos y biosimilares están entrando en el mercado.
- Los avances en las formulaciones tópicas tienen como objetivo mejorar la eficacia terapéutica.
Conclusiones:
- La investigación en curso se centra en optimizar los tratamientos existentes y desarrollar nuevos medicamentos.
- Las innovaciones ofrecen mejores opciones de tratamiento y resultados clínicos sostenidos para los pacientes con psoriasis.
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