Video Experimental Relacionado

Updated: Sep 9, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

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El factor de crecimiento transformador beta (TGF-β) induce la señalización de interferón tipo 1 en los queratinocitos

Christopher W Wasson1, Sophie L Dibb2, Begoña Caballero-Ruiz2

  • 1Faculty of Medicine and Health, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. c.w.wasson@leeds.ac.uk.

Arthritis research & therapy
|September 2, 2025
PubMed
Resumen

La esclerosis sistémica (SSc) incluye fibrosis cutánea y daño a los órganos internos. Este estudio revela que el canal intracelular de cloruro 4 (CLIC4) es crucial para la señalización aberrante de interferón tipo 1 observada en la piel SSc.

Palabras clave:
CLIC4 (en inglés)El InterferónSTAT1 (en inglés)La esclerodermia

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