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Microangiopatía trombótica asociada con carfilzomib en un paciente con mieloma múltiple: impacto de las alteraciones
Joana Lopes1, Vítor Fernandes1, Nuria Paulo1
1Nephrology Department, Unidade Local de Saúde São João, Porto, PRT.
Cureus
|September 2, 2025
Resumen
El tratamiento con carfilzomib puede causar raramente microangiopatía trombótica y lesión renal aguda. El tratamiento inmediato con eculizumab, especialmente en pacientes genéticamente predispuestos, puede conducir a una recuperación completa.
Área de la Ciencia:
- Nefrología
- Hematología
- Farmacología
Sus antecedentes:
- El carfilzomib es un inhibidor del proteasoma para el mieloma múltiple recurrente/ refractario.
- Aunque es eficaz, el carfilzomib tiene efectos secundarios raros y graves.
- La microangiopatía trombótica y la lesión renal aguda son posibles complicaciones.
Palabras clave:
lesión renal agudaCarfilzomib y sus derivadosLos efectos secundarios de las drogasMieloma múltiplemicroangiopatía trombóticaMás Videos Relacionados
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