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Los implantes mamarios de silicona como causa oculta de la fiebre: una trampa en el diagnóstico

Kotaro Kunitomo¹, Fumitaka Yoshimura¹, Junko Kubosaki¹

¹General Medicine, National Hospital Organization Kumamoto Medical Center, Kumamoto, JPN.

|September 2, 2025

Resumen

Una mujer con fiebre inexplicable y elevación de la PCR después de la ureterolitotripsia fue diagnosticada con síndrome autoinmune/inflamatorio inducido por adyuvantes (ASIA). Los síntomas se resolvieron después de la extracción de los implantes mamarios de silicona, destacando la importancia de considerar la ASIA en casos de inflamación sistémica.

Área de la Ciencia:

Inmunología
Radiología
Reumatología

Sus antecedentes:

El síndrome autoinmune / inflamatorio inducido por adyuvantes (ASIA) es una condición rara desencadenada por adyuvantes como la silicona.
El diagnóstico puede ser difícil, especialmente sin síntomas locales en el sitio del implante.

Objetivo del estudio:

Para investigar la causa de la inflamación sistémica persistente sin explicación.
Evaluar el papel de los implantes mamarios de silicona en los síntomas de la paciente.
Para resaltar la utilidad diagnóstica de la resonancia magnética en la sospecha de síndrome autoinmune/inflamatorio inducido por adyuvantes (ASIA).

Principales métodos:

Imágenes por resonancia magnética de los implantes mamarios.
Evaluación clínica, incluido examen físico y evaluación de los síntomas.
Extirpación quirúrgica de los implantes mamarios bilaterales de silicona.

Principales resultados:

La resonancia magnética reveló una ruptura intracapsular del implante mamario izquierdo.
El paciente cumplió con los criterios diagnósticos para la ASIA (exposición a silicona, síntomas sistémicos, resolución de los síntomas después del trasplante).
Los síntomas desaparecieron por completo tras la extirpación bilateral del implante.

Conclusiones:

El síndrome autoinmune/inflamatorio inducido por adyuvantes (ASIA) es una causa potencial de inflamación sistémica inexplicable en pacientes con implantes de silicona.
El diagnóstico de ASIA puede ser difícil sin síntomas locales en el sitio del implante.
La resonancia magnética es crucial para identificar la ruptura del implante y orientar el diagnóstico y el tratamiento de la ASIA.

Palabras clave:

Síndrome autoinmune/inflamatorio inducido por adyuvantes (asia)fiebre de origen desconocido Resonancia magnética peligro potencial para el diagnóstico erróneo Implante mamario de silicona

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