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Las lesiones bilaterales del globo pálido asociadas con el COVID-19: imitan el envenenamiento agudo por monóxido de
Jun Hyeon Park1, Kyung Sik Yi1,2, Chi-Hoon Choi1,2
1Department of Radiology, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Medicine
|September 3, 2025
Resumen
Las lesiones simétricas bilaterales del globo pálido son un hallazgo raro en la encefalopatía por COVID-19. Este caso destaca las pistas de imágenes que pueden ayudar a diferenciarlo del envenenamiento por monóxido de carbono.
Área de la Ciencia:
- Neurología
- Enfermedades infecciosas
- Radiología
Sus antecedentes:
- La participación del globo pálido simétrico bilateral (GP) es un hallazgo extremadamente raro en la encefalopatía relacionada con el COVID-19.
- Distinguir la encefalopatía COVID-19 con lesiones generales de la intoxicación por monóxido de carbono presenta desafíos de diagnóstico.
Objetivo del estudio:
- Para informar un caso raro de lesiones simétricas bilaterales del globo pálido en un paciente con COVID-19.
- Para identificar las pistas radiológicas potenciales para diferenciar la encefalopatía COVID-19 de la intoxicación por monóxido de carbono.
Principales métodos:
- Un hombre de 76 años con neumonía por COVID-19 presentó un estado mental alterado.
- La resonancia magnética cerebral reveló lesiones simétricas de alta intensidad de señal en el GP bilateral.
- El paciente recibió atención de apoyo, incluyendo oxígeno, norepinefrina, meropenem y remdesivir.
Principales resultados:
- El paciente mostró una recuperación neurológica gradual con la resolución de las lesiones en la RM de seguimiento.
- Los síntomas iniciales de neumonía mejoraron, pero el estado mental alterado persistió inicialmente.
Conclusiones:
- Las lesiones GP simétricas bilaterales en la encefalopatía por COVID-19 pueden imitar la intoxicación por monóxido de carbono.
- La presencia de múltiples lesiones isquémicas, comunes en el COVID-19 pero raras en la intoxicación por CO, puede ayudar en el diagnóstico diferencial.
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