Video Experimental Relacionado

Updated: Sep 9, 2025

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae
09:40

Quantitation and Analysis of the Formation of HO-Endonuclease Stimulated Chromosomal Translocations by Single-Strand Annealing in Saccharomyces cerevisiae

Published on: September 23, 2011

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Complejo hnRNPL-CstF64: coordinación de CSR y LSR en la dinámica de recombinación del locus de IgH a través de la

Farazul Haque1, Mikiyo Nakata1, Hidetaka Kosako2

  • 1Department of Immunology and Genomic Medicine, Centre for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.

Nucleic acids research
|September 3, 2025
PubMed
Resumen

La ribonucleoproteína L heterogénea (hnRNPL) regula la diversificación de anticuerpos formando un complejo que mejora la transcripción del ARN potenciador y la reparación del ADN. Este descubrimiento vincula la transcripción de ARN a la reparación del ADN en la recombinación del interruptor de clase y la recombinación del suicidio del locus.

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