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Determinantes sociales asociados con el diagnóstico avanzado del cáncer de mama
Madonna A Fekry1,2, Loay Kassem3,4, Justin C Yang2,5,6
1Clinical Research Department, Cairo Oncology Center, Cairo, Egypt.
JCO global oncology
|September 3, 2025
Resumen
Los pacientes egipcios con cáncer de mama a menudo presentan enfermedad avanzada. El desempleo y la residencia rural son factores clave asociados con el diagnóstico tardío, lo que pone de relieve la necesidad de aumentar la conciencia pública y las iniciativas de detección temprana.
Área de la Ciencia:
- En el campo de la oncología
- Salud pública
- Epidemiología
Sus antecedentes:
- El cáncer de mama (BC) se diagnostica con frecuencia en etapas avanzadas en Egipto.
- Comprender los factores que contribuyen a la presentación tardía es crucial para mejorar los resultados de los pacientes.
Objetivo del estudio:
- Investigar los factores sociodemográficos y clínicos asociados con la presentación de cáncer de mama en estadio avanzado en pacientes egipcias.
- Identificar los principales factores predictivos del diagnóstico tardío para las intervenciones específicas.
Principales métodos:
- Un estudio de cohorte retrospectivo analizó los datos de 1.953 pacientes de cáncer de mama egipcios diagnosticados entre 2011 y 2020.
- Se utilizaron modelos de regresión logística para evaluar las asociaciones entre las características del paciente y la BC en estadio avanzado.
Principales resultados:
- Más del 43% de las pacientes fueron diagnosticadas con cáncer de mama en estadio avanzado.
- El análisis multivariable identificó el desempleo (aOR, 1.44) y la residencia rural (aOR, 1.88) como factores significativos asociados con el BC avanzado.
- Un Ki67% más alto (aOR, 1, 01) también se relacionó con la presentación avanzada de la enfermedad.
Conclusiones:
- El desempleo y la residencia rural están fuertemente asociados con el diagnóstico de cáncer de mama avanzado en Egipto.
- Las campañas de sensibilización del público son esenciales para promover la detección temprana del cáncer de mama.
- Los programas de detección y apoyo dirigidos a las poblaciones vulnerables pueden mejorar las tasas de diagnóstico temprano.
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