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Updated: Sep 9, 2025

Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells
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Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

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La transcitosis de LDL pasa a través de la red trans-Golgi y requiere Rab10

Tse Wing Winnie Ho1, Changsen Wang2, Warren L Lee3

  • 1Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada.

Journal of lipid research
|September 3, 2025
PubMed
Resumen

La transcitosis de lipoproteínas de baja densidad (LDL) involucra el aparato de Golgi, con las proteínas Rab que regulan este proceso. Las proteínas Rab específicas, Rab6a y Rab10, son cruciales para el transporte de LDL a través de las células endoteliales.

Palabras clave:
La aterosclerosisEl aparato de GolgiEl colesterol bajoLas lipoproteínasEn el caso de losEn el caso de losLa transcitosisBiología vascular

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