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La proteína del dedo de zinc ZNF638 en la grasa marrón deteriora la diabetes tipo 1 a través de la proteína de unión

Meiyao Meng¹, Shuang Liu², Yinzhao Zhong²

¹Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai 200241, China; Joint Center for Translational Medicine, Shanghai Fifth People's Hospital, Fudan University and School of Life Science, East China Normal University, Shanghai 200241, China.

Science bulletin

|September 3, 2025

Resumen

No abstract available in PubMed .

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...