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Síndrome post-COVID en pacientes sintomáticos con COVID-19: un estudio de cohorte retrospectivo
Nhu Ngoc Nguyen1,2, Hervé Tissot-Dupont1,3, Philippe Brouqui1,3
1Aix Marseille University, AP-HM, SSA, RITMES, Marseille, France.
BMC infectious diseases
|September 3, 2025
Resumen
Los síntomas de COVID prolongado, incluidos los problemas neurológicos y la astenia, son comunes. Los pacientes masculinos con fiebre o trastornos del gusto durante el COVID-19 agudo enfrentan un mayor riesgo de síntomas persistentes.
Área de la Ciencia:
- Investigaciones médicas
- Enfermedades infecciosas
- Salud pública
Sus antecedentes:
- Las condiciones post-COVID, o COVID largo, presentan un desafío significativo con factores de riesgo y plazos de recuperación poco claros.
- Comprender la persistencia de los síntomas es crucial para controlar el impacto a largo plazo de la infección por SARS-CoV-2.
Objetivo del estudio:
- Para investigar la prevalencia de los síntomas después de la COVID-19 aguda.
- Identificar los factores de riesgo asociados con la persistencia de los síntomas de la COVID.
Principales métodos:
- Estudio de cohorte retrospectivo que analiza los registros médicos de 319 personas después de la COVID.
- Seguimiento durante al menos seis meses, incluidos exámenes especializados.
- Análisis descriptivo y de regresión logística para determinar la prevalencia y los factores de riesgo.
Principales resultados:
- Los síntomas neurológicos, astenia y cardiorespiratorios fueron los más frecuentes entre los síntomas persistentes.
- Aproximadamente el 80-81% de los pacientes mostraron mejoría de los síntomas entre los seis y los doce meses.
- El sexo masculino, la fiebre y los trastornos del gusto durante el COVID-19 agudo fueron factores de riesgo independientes para la persistencia de los síntomas.
Conclusiones:
- Es posible identificar a los pacientes de alto riesgo para el COVID prolongado persistente.
- Se pueden desarrollar intervenciones terapéuticas específicas para las personas en riesgo.
Palabras clave:
El COVID-19COVID largoDespués de la COVIDRecuperaciónFactores de riesgoEn el caso del SARS-CoV-2Más Videos Relacionados
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