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Updated: Sep 9, 2025
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Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
Published on: November 15, 2024
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[Caso de disfunción de varios órganos causado por el glifosato agudo combinado con envenenamiento por alcohol]
1Emergency Department of the Second People's Hospital of Guiyang, Guiyang 550081, China.
Resumen
La intoxicación aguda por el pesticida glifosato y la coingestión de alcohol pueden causar el síndrome de disfunción múltiple de órganos (MODS). Los cuidados de apoyo y las terapias como la terapia de reemplazo renal continua (CRRT) mejoraron la supervivencia del paciente.
Área de la Ciencia:
- Toxicología
- Medicina Clínica
- Medicina de emergencia
Sus antecedentes:
- La ingestión simultánea de plaguicidas y alcohol presenta un desafío toxicológico significativo.
- La toxicidad del glifosato-isopropil amonio y el etanol puede provocar efectos sistémicos graves.
Objetivo del estudio:
- Analizar la presentación clínica y el tratamiento de un paciente con intoxicación aguda por glifosato y etanol.
- Resaltar el desarrollo del síndrome de disfunción múltiple de órganos (MODS) en este contexto.
Principales métodos:
- Análisis de los datos clínicos en el informe de caso.
- Examen detallado de los hallazgos diagnósticos y las intervenciones terapéuticas.
- Centrarse en el cuidado de apoyo, la terapia de reemplazo renal continua (CRRT) y la hemoperfusión (HP).
Principales resultados:
- El paciente desarrolló MODS, incluyendo lesión renal aguda (AKI), acidosis metabólica, hipercalemia, lesión pulmonar aguda (ALI), lesión hepática aguda, lesión intestinal aguda y síndrome de respuesta inflamatoria sistémica (SIRS).
- La recuperación exitosa y la descarga completa se lograron con la combinación de cuidados de apoyo, CRRT y HP.
Conclusiones:
- El envenenamiento agudo por glifosato y etanol combinado es una afección grave que puede inducir el MODS.
- Un tratamiento eficaz que incluya cuidados intensivos de apoyo y terapias extracorporales puede mejorar los resultados y las tasas de supervivencia de los pacientes.
Palabras clave:
Envenenamiento por alcoholTerapia de reemplazo renal continuaEnvenenamiento por glifosatoLa hemoperfusiónSíndrome de disfunción múltiple de órganosEnvenenamientoMás Videos Relacionados
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