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Parestesia reportada por pacientes después de la administración de suzetrigina: un informe de caso

Daniel Adams¹, Mary Bailey¹

¹Western Reserve Hospital -Center for Pain Medicine, Cuyahoga Falls, Ohio, USA.

Journal of pain & palliative care pharmacotherapy

|September 4, 2025

Resumen

La suzetrigina, un nuevo analgésico no opioide, es eficaz para el dolor agudo. Un estudio de caso informa de parestesia, un nuevo efecto secundario, en un paciente con dolor postoperatorio refractario.

Área de la Ciencia:

Farmacología
Medicina Clínica
Tratamiento del dolor

Sus antecedentes:

La suzetrigina es un nuevo analgésico no opioide de primera clase.
Está indicado para el dolor agudo de moderado a severo, especialmente el dolor postoperatorio.
En ensayos clínicos iniciales se informó de dolores de cabeza y estreñimiento como efectos secundarios comunes.

Objetivo del estudio:

Para reportar un efecto secundario previamente no documentado de suzetrigina.
Resaltar los posibles efectos adversos asociados a un uso más amplio del fármaco después de su comercialización.
Para describir un caso de parestesia en un paciente que recibe suzetrigina.

Principales métodos:

Presentación del informe del caso.
Revisión del historial médico del paciente y administración de fármacos.
Observación clínica y documentación de los efectos adversos.

Principales resultados:

El paciente experimentó parestesia después de la administración de suzetrigina para el dolor postoperatorio refractario.
Este efecto secundario no se identificó en los ensayos clínicos previos a la comercialización.
No se notificaron otros problemas no previstos en la vigilancia inicial posterior a la comercialización.

Conclusiones:

El uso clínico más amplio de suzetrigina puede revelar efectos secundarios adicionales.
La parestesia es un evento adverso potencial asociado con la suzetrigina.
La farmacovigilancia continua es crucial para los nuevos analgésicos como la suzetrigina.

Palabras clave:

Parestesia, por ejemplo Dolor después de la operación efectos secundarios canales de sodio Susetrigina y sus derivados

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