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Actividad física antes del tromboembolismo venoso y riesgo de recurrencia en una cohorte de inicio basada en la
Anna C Frauenheim1, Kerri L Wiggins2, Rozenn N Lemaitre2
1Department of Epidemiology, University of Washington, 1410 NE Campus Pkwy, Seattle, WA, 98195, USA. afrauen@uw.edu.
Journal of thrombosis and thrombolysis
|September 4, 2025
Resumen
La actividad física regular de moderada a vigorosa no pareció reducir el riesgo de tromboembolismo venoso recurrente (TEV). Este estudio no encontró ninguna asociación entre los niveles de MVPA y la recurrencia de TEV en adultos que habían tenido un evento anterior de TEV.
Área de la Ciencia:
- Salud cardiovascular
- Fisiología del ejercicio
- Investigación de la trombosis
Sus antecedentes:
- La relación entre la actividad física y el tromboembolismo venoso recurrente (TEV) requiere más investigación.
- La comprensión de esta asociación podría informar las directrices de salud pública y las recomendaciones para los pacientes.
Objetivo del estudio:
- Examinar la asociación entre la actividad física de moderada a vigorosa (AVMV) y el riesgo de TEV recurrente.
- Determinar si los niveles de MVPA previos a la TEV influyen en la recurrencia de la misma en adultos.
Principales métodos:
- Se realizó un estudio de cohorte con 1381 adultos con TEV incidente.
- La actividad física moderada a vigorosa (AVMV) fue autoinformada y cuantificada en horas MET por semana.
- Se utilizaron modelos de riesgos proporcionales de Cox para analizar el riesgo de recurrencia de TEV.
Principales resultados:
- No se encontró una asociación significativa entre cualquier MVPA versus ninguna y la recurrencia de TEV (HRadj=1,24).
- Entre los pacientes con MVPA, ni las horas/semana continuas de MET ni los cuartiles mostraron un vínculo con la recurrencia de TEV.
- Los análisis secundarios de intensidad moderada y intensa de PA tampoco revelaron asociación con la recurrencia.
Conclusiones:
- La MVPA autoinformada antes de un evento de TEV no se asoció con un riesgo reducido de recurrencia de TEV.
- Los hallazgos actuales sugieren que los niveles de actividad física pueden no ser un factor significativo en la recurrencia de TEV.
- Se necesita más investigación para explorar otros posibles factores de riesgo modificables para la recurrencia de TEV.
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