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Normas metodológicas para la realización de revisiones sistemáticas de alta calidad

Alessandro De Cassai1,2, Burhan Dost3, Serkan Tulgar4

  • 1Department of Medicine (DIMED), University of Padua, 35127 Padua, Italy.

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Resumen
Este resumen es generado por máquina.

Esta guía detalla la realización de revisiones sistemáticas de alta calidad en ciencias biológicas, adaptando los principios de la investigación clínica. Abarca el desarrollo de protocolos, las estrategias de búsqueda, la extracción de datos, la evaluación de sesgos y la presentación de informes utilizando las directrices de PRISMA 2020 para la síntesis de evidencia transparente.

Palabras clave:
ClasificaciónPRISMA (en inglés)Síntesis de las pruebaslas directricesMetanálisissíntesis narrativaDesviación de la publicaciónriesgo de sesgoSelección del estudioanálisis sistemático

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Área de la Ciencia:

  • Biología, salud y ciencias sociales
  • Adaptación de los principios de la investigación clínica a las ciencias biológicas (ecología, biología molecular, biología evolutiva)

Sus antecedentes:

  • Las revisiones sistemáticas son cruciales para la investigación basada en la evidencia.
  • Las directrices existentes se centran principalmente en la investigación clínica.

Objetivo del estudio:

  • Proporcionar una guía detallada para llevar a cabo revisiones sistemáticas de alta calidad en las ciencias biológicas.
  • Adaptar y traducir los principios de revisión basados en la evidencia para los campos de investigación biológica.

Principales métodos:

  • Desarrollo y registro del protocolo
  • Diseño integral de la estrategia de búsqueda y selección del estudio
  • Extracción de datos, evaluación del riesgo de sesgo, metanálisis y síntesis narrativa
  • Utilización de marcos como GRADE para la certeza de las pruebas y PRISMA 2020 para la presentación de informes

Principales resultados:

  • Describe las etapas clave para la síntesis de pruebas transparentes y reproducibles.
  • Destaca metodologías, desafíos y recursos específicos para las ciencias biológicas.
  • Hace hincapié en la extracción precisa de datos y herramientas validadas para la evaluación de sesgos.

Conclusiones:

  • Proporciona orientación personalizada para los investigadores en las ciencias biológicas.
  • Facilita la realización de síntesis de pruebas transparentes y reproducibles en biología.
  • Mejora la aplicación de los principios de revisión sistemática en las diversas disciplinas científicas.