Video Experimental Relacionado
Updated: Sep 9, 2025
03:19
Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
494
Dinámica de los micronutrientes y riesgo de deficiencia durante el embarazo y después del parto en una cohorte
Alexandra Kristufkova1, Neha Basheer2, Katarina Koprdova3
11st Department of Obstetrics and Gynecology, St. Cyril and Method's Hospital, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.
PloS one
|September 4, 2025
Resumen
Los niveles maternos de vitaminas y oligoelementos fluctúan significativamente durante el embarazo y el posparto. Las deficiencias de vitamina B12, hierro y vitamina D son comunes, lo que pone de relieve la necesidad de monitorear durante y después del embarazo.
Área de la Ciencia:
- Obstetricia y ginecología
- Ciencias de la nutrición
- La bioquímica clínica
Sus antecedentes:
- El estado de los micronutrientes maternos es crítico tanto para el desarrollo fetal como para la salud materna.
- El embarazo y el período posparto están asociados con cambios fisiológicos significativos que pueden afectar los niveles de nutrientes.
- Comprender estas dinámicas es esencial para optimizar la atención prenatal y postnatal.
Objetivo del estudio:
- Investigar los cambios en las concentraciones sanguíneas de vitaminas clave, oligoelementos y homocisteína durante el embarazo y el período posparto.
- Para identificar los micronutrientes específicos con fluctuaciones o deficiencias significativas.
- Evaluar la utilidad del análisis de manchas de sangre seca (DBS) en comparación con el muestreo de sangre venosa tradicional.
Principales métodos:
- Se realizó un estudio de cohorte nacional transversal en Eslovaquia entre enero y junio de 2024.
- Se recogieron muestras de sangre venosa y de sangre capilar seca de mujeres embarazadas y posparto.
- Se emplearon métodos bioquímicos y biofísicos estándar para el análisis de micronutrientes, incluidas las vitaminas A, B6, B12, D, E, selenio, magnesio, zinc, hierro (transferrina) y homocisteína.
Principales resultados:
- Se observaron diferencias significativas en los niveles de micronutrientes maternos en las etapas de embarazo y posparto.
- Se observaron niveles más bajos de vitamina A, B12, hierro y zinc durante el embarazo, mientras que los niveles de vitamina E fueron más altos.
- Se identificó una alta prevalencia de deficiencias de vitamina B12, hierro y vitamina D, especialmente en el tercer trimestre y después del parto. El análisis de DBS mostró resultados comparables a la sangre venosa para la vitamina A, D y homocisteína.
Conclusiones:
- Los perfiles de micronutrientes maternos experimentan cambios dinámicos durante el embarazo y el período posparto.
- Las deficiencias específicas, especialmente en vitamina B12, hierro y vitamina D, requieren atención y monitoreo.
- La tecnología de las manchas de sangre seca ofrece una alternativa viable y comparable para evaluar ciertos niveles de micronutrientes, lo que podría simplificar la recogida de muestras.
Más Videos Relacionados
08:45Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
2.1K
03:35Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
Published on: December 1, 2023
377
Videos de Conceptos Relacionados
01:30Vitamins
979
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
979
02:35Key Elements for Plant Nutrition
21.1K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
21.1K
01:27Mineral, Vitamin and Water Absorption
703
Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
703
01:28Microbial Nutrition
280
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
280
01:07Teratogenicity
2.7K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.7K
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
407
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
407