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Recomendaciones para estudiar la relación entre el diagnóstico de cáncer y el intervalo de tratamiento y la
Matthew Jalink1,2, Will D King3, Benjamin O Anderson4
1Department of Public Health Sciences, Queen's University, Kingston, ON, Canada. matt.jalink@queensu.ca.
British journal of cancer
|September 4, 2025
Resumen
Comprender el tiempo desde el diagnóstico del cáncer hasta el tratamiento (DTI) es crucial para la supervivencia del paciente (OS). Este estudio proporciona recomendaciones de consenso de expertos para mejorar los métodos de investigación, asegurando una evidencia precisa sobre el DTI.
Área de la Ciencia:
- En el campo de la oncología
- Epidemiología
- Investigación en servicios de salud
Sus antecedentes:
- El retraso en el inicio del tratamiento contra el cáncer (DTI) está relacionado con peores resultados de supervivencia.
- La investigación existente sobre la DTI y la supervivencia global (OS) está confundida por sesgos y metodologías variadas.
Objetivo del estudio:
- Establecer directrices basadas en el consenso para el estudio de la asociación entre DTI y OS.
- Mejorar el rigor metodológico de la investigación sobre los retrasos en el tratamiento del cáncer.
Principales métodos:
- Un enfoque Delphi modificado que involucra a un panel de expertos multidisciplinarios.
- Tres rondas de construcción de consenso para generar recomendaciones.
- Inclusión de expertos en epidemiología, bioestadística, oncología y política de salud.
Principales resultados:
- Se elaboró una lista exhaustiva de 24 recomendaciones de consenso.
- Las recomendaciones cubren la definición de variables, la creación de cohorte, el control de sesgo y el análisis.
- Se logró un consenso de expertos sobre las mejores prácticas para la investigación del DTI-OS.
Conclusiones:
- Los enfoques metodológicos rigurosos son esenciales para una investigación DTI-OS válida.
- Estas recomendaciones tienen por objeto mejorar la calidad de los estudios futuros.
- La investigación mejorada informará las decisiones basadas en la evidencia sobre los tiempos de espera óptimos para el cáncer.
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