Video Experimental Relacionado
Updated: Jun 16, 2026
08:26
Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
15.1K
¿Se puede utilizar el glicerol como un medio de almacenamiento alternativo eficaz para los dientes extraídos antes de
Saumya Taneja1, Rajeev K Singh2, Khushtar Haider3
1Department of Pedodontics and Preventive Dentistry, Inderprastha Dental College & Hospital, Ghaziabad, IND.
Cureus
|September 5, 2025
Resumen
El glicerol se muestra prometedor como medio de almacenamiento a corto plazo para los dientes avulsos, preservando la vitalidad celular del ligamento periodontal (PDL). Una solución de glicerol al 10% demostró su eficacia, aunque Hank
Área de la Ciencia:
- La endodoncia
- Traumatología dental
- Biología celular
Sus antecedentes:
- La preservación de la vitalidad de las células del ligamento periodontal (LPD) es crucial para el éxito de la reimplantación de un diente avulso.
- Los medios de almacenamiento actuales para los dientes abultados tienen limitaciones.
- El glicerol, un agente crioprotector conocido, no ha sido evaluado para el almacenamiento de dientes avulsos.
Objetivo del estudio:
- Evaluar el glicerol como medio de almacenamiento para los dientes humanos avulsos.
- Para comparar la eficacia de las diferentes concentraciones de glicerol con la solución salina equilibrada de Hank (HBSS).
Principales métodos:
- Se obtuvieron células del ligamento periodontal (PDL) de dientes humanos (de 8 a 15 años) y se cultivaron.
- Los cultivos celulares fueron expuestos a la solución salina balanceada de Hank (HBSS), al 10% de glicerol y al glicerol puro durante 1, 6, 12 y 24 horas a 37°C.
- Se evaluó la viabilidad celular y se analizaron estadísticamente los datos utilizando ANOVA unidireccional y la prueba post hoc de Tukey.
Principales resultados:
- La solución salina equilibrada de Hank (HBSS) demostró la mayor viabilidad celular.
- El 10% de glicerol mostró una viabilidad celular significativamente mayor en comparación con el glicerol puro.
- El glicerol puro resultó en la viabilidad celular más baja.
Conclusiones:
- El 10% de glicerol es un medio eficaz de almacenamiento a corto plazo para los dientes abultados.
- Se recomienda realizar más investigaciones sobre las diferentes concentraciones de glicerol y su eficacia clínica.
Videos de Conceptos Relacionados
01:10Sugars as Energy Storage Molecules
Sugar (a simple carbohydrate) metabolism (chemical reactions) is a classic example of the many cellular processes that use and produce energy. Living things consume sugar as a major energy source because sugar molecules have considerable energy stored within their bonds. Consumed carbohydrates have their origins in photosynthesizing organisms like plants. During photosynthesis, plants use the energy of sunlight to convert carbon dioxide gas into sugar molecules, like glucose. Because this...
01:10Sugars as Energy Storage Molecules
Sugar (a simple carbohydrate) metabolism (chemical reactions) is a classic example of the many cellular processes that use and produce energy. Living things consume sugar as a major energy source because sugar molecules have considerable energy stored within their bonds. Consumed carbohydrates have their origins in photosynthesizing organisms like plants. During photosynthesis, plants use the energy of sunlight to convert carbon dioxide gas into sugar molecules, like glucose. Because this...
01:19Depolarizing Blockers: Pharmocokinetics
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
01:30Local Anesthetics: Chemistry and Structure-Activity Relationship
Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
01:23Local Anesthetics: Common Agents and Their Applications
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
01:18Drug Delivery: Enteral Route
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
Drugs in...
Drugs in...