Video Experimental Relacionado

Updated: Sep 9, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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As48, un primer modulador TREM2 de doble función: activación de los receptores y inhibición del derramamiento

Sungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay

    bioRxiv : the preprint server for biology
    |September 5, 2025
    PubMed
    Resumen

    Un nuevo medicamento, As48, activa la señalización TREM2 y previene su eliminación, ofreciendo una nueva estrategia terapéutica para la enfermedad de Alzheimer al mejorar la función microglial y los mecanismos de reparación del cerebro.

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