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[Rabdomiolisis paraneoplásica] Se ha desarrollado
Carlo Schneider1,2, Patricia Faßbender3,4, Linus Völker3,5
1Klinik für Allgemeine Innere Medizin und Altersmedizin, Evangelisches Klinikum Köln Weyertal, Weyertal 76, 50931, Köln, Deutschland. carlo.schneider@klinikum-weyertal.de.
Innere Medizin (Heidelberg, Germany)
|September 5, 2025
Resumen
La hipocalemia grave, una causa rara de rabdomiolisis, se relacionó con el hiperaldosteronismo en un paciente con un carcinoma suprarrenal. El diagnóstico rápido y la suplementación con potasio mejoraron los síntomas, destacando la importancia de considerar el hiperaldosteronismo en casos similares.
Área de la Ciencia:
- Endocrinología
- Nefrología
- En el campo de la oncología
Sus antecedentes:
- El dolor muscular y el deterioro general de la salud pueden ser indicios de trastornos metabólicos subyacentes.
- La hipocalemia grave es un desequilibrio electrolítico crítico que puede manifestarse con síntomas musculares significativos.
- El hiperaldosteronismo es una condición caracterizada por una producción excesiva de aldosterona, que conduce a anormalidades en los electrolitos.
Objetivo del estudio:
- Para investigar el vínculo entre la rabdomiolisis, la hipocalemia severa y un trastorno endocrino subyacente.
- Para resaltar el hiperaldosteronismo como una causa rara pero crítica de la rabdomiolisis.
- Para reportar un caso de carcinoma suprarrenal presentado con rabdomiolisis inducida por hipocalemia.
Principales métodos:
- Presentación clínica de una mujer de 49 años con dolor muscular y salud en declive.
- El análisis de laboratorio reveló rabdomiolisis y hipocalemia severa.
- Examen de diagnóstico que incluya ecografía y posterior extirpación quirúrgica y diagnóstico patológico de una masa suprarrenal.
Principales resultados:
- Los síntomas de los pacientes mejoraron significativamente con la suplementación con potasio.
- Se identificó el hiperaldosteronismo como la causa de la hipocalemia severa.
- Una masa suprarrenal fue diagnosticada como carcinoma suprarrenal después de la cirugía.
Conclusiones:
- La hipocalemia grave puede ser un síntoma raro de la rabdomiolisis.
- El hiperaldosteronismo debe considerarse en el diagnóstico diferencial de la rabdomiolisis inducida por hipocalemia.
- Las masas suprarrenales, incluido el carcinoma suprarrenal, pueden manifestarse con trastornos endocrinos como el hiperaldosteronismo.
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