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Agentes hemostáticos a base de arcilla: fabricación, mecanismos y pruebas

Yanhuai Ding¹, Dan Qian¹, Jiafeng Liang¹

¹School of Mechanical Engineering and Mechanics, Xiangtan University, Xiangtan 411105, China.

Biomaterials advances

|September 5, 2025

Resumen

Los agentes hemostáticos a base de arcilla ofrecen un control rápido de la hemorragia en lesiones graves. Estos agentes minerales mejoran la coagulación natural, mejorando la supervivencia en medicina de emergencia y de combate.

Área de la Ciencia:

Ciencias de los materiales
Ingeniería biomédica
Medicina de emergencia

Sus antecedentes:

El control hemorrágico es crítico en emergencias y traumas de combate.
Los métodos convencionales tienen limitaciones para sangrado severo o complejo.
Los agentes hemostáticos a base de minerales ofrecen una alternativa prometedora.

Objetivo del estudio:

Para revisar los agentes hemostáticos derivados de la arcilla.
Examinar su fabricación, mecanismos y aplicaciones.
Proporcionar un marco para optimizar su uso.

Principales métodos:

Revisión sistemática de la literatura.
Análisis de las estructuras cristalinas y de las propiedades fisicoquímicas.
Evaluación de las medidas de rendimiento hemostático.

Principales resultados:

Los agentes a base de arcilla aprovechan el intercambio catiónico y la carga superficial para la coagulación.
Se detallan los métodos de fabricación y los mecanismos moleculares.
Se analizan las aplicaciones clínicas y los datos de rendimiento.

Conclusiones:

Los hemostatos de arcilla representan un avance en el tratamiento de heridas.
Las investigaciones adicionales pueden optimizar los materiales para mejorar la hemostasis.
Esta revisión guía el desarrollo futuro de sistemas hemostáticos compuestos.

Palabras clave:

Hemoestáticos derivados de arcilla Metodologías de fabricación La hemostasis Mecanismos hemostáticos Propiedades físico-químicas

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