Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Channel Rhodopsins01:11

Channel Rhodopsins

2.6K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
2.6K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.5K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

7.5K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.5K
The Retina01:32

The Retina

70.4K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
70.4K
The Photochemical Reaction Center01:29

The Photochemical Reaction Center

4.3K
Reaction centers are pigment-protein complexes that initiate energy conversion from photons to chemical entities. Therefore, photochemical reaction center is a more appropriate term that describes these complexes. The Nobel laureates Robert Emerson and William Arnold provided the first experimental evidence of photochemical reaction centers by demonstrating the participation of nearly 2,500 chlorophyll molecules for the release of just one molecule of oxygen. Despite thousands of photosynthetic...
4.3K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Selenoprotein thioredoxin reductase 1 promotes cancer cells ferroptosis by suppressing GPX4 expression.

Cell death and differentiation·2026
Same author

Structural basis of protease-activated receptor 2 activation and biased agonism.

Cell discovery·2025
Same author

Cryo-EM structure of a nanobody-bound heliorhodopsin.

Biochemical and biophysical research communications·2025
Same author

Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Structural insight into GPR55 ligand recognition and G-protein coupling.

Cell research·2024
Same author

Insights into lysophosphatidylserine recognition and Gα<sub>12/13</sub>-coupling specificity of P2Y10.

Cell chemical biology·2024

Video Experimental Relacionado

Updated: Sep 8, 2025

Author Spotlight: Unraveling Vitamin A Transport Mechanisms &#8212; Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
08:18

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions

Published on: October 4, 2024

1.2K

Conocimientos estructurales sobre las rodopsinas microbianas libres de retina

Zhenmei Xu1, Yuanzheng He1

  • 1HIT Center for Life Sciences, School of Life Science and Technology, Faculty of Life Sciences and Medicine, Harbin Institute of Technology, Harbin 150001, China; Frontiers Science Center for Matter Behave in Space Environment, Harbin Institute of Technology, Harbin 150001, China.

Structure (London, England : 1993)
|September 5, 2025
PubMed
Resumen

Este estudio revela la estructura de una rodopsina asociada a la flotilina libre de retina (FArhodopsin). Los hallazgos ofrecen nuevos conocimientos sobre la arquitectura de estas rodopsinas únicas y sus posibles funciones no relacionadas con la luz.

Más Videos Relacionados

A Rhodopsin Transport Assay by High-Content Imaging Analysis
12:11

A Rhodopsin Transport Assay by High-Content Imaging Analysis

Published on: January 16, 2019

6.6K
Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
09:19

Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization

Published on: March 16, 2020

7.1K

Videos de Experimentos Relacionados

Last Updated: Sep 8, 2025

Author Spotlight: Unraveling Vitamin A Transport Mechanisms &#8212; Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
08:18

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions

Published on: October 4, 2024

1.2K
A Rhodopsin Transport Assay by High-Content Imaging Analysis
12:11

A Rhodopsin Transport Assay by High-Content Imaging Analysis

Published on: January 16, 2019

6.6K
Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
09:19

Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization

Published on: March 16, 2020

7.1K

Área de la Ciencia:

  • Biología estructural
  • La bioquímica
  • Proteínas de membrana

Sus antecedentes:

  • Las rodopsinas son proteínas fotorreceptoras que normalmente utilizan un cofactor retiniano para capturar la energía de la luz.
  • La evolución ha llevado al surgimiento de rodopsinas que carecen de esta capacidad canónica de detección de luz.
  • Las rodopsinas asociadas a la flotilina (FArhodopsins) representan una clase de rodopsinas con una función desconocida debido a la ausencia de retina.

Objetivo del estudio:

  • Determinar la estructura tridimensional de una rodopsina sin flotilina asociada a la retina (FArhodopsina).
  • Para aclarar la base estructural de la ausencia de retina en las Farodopsinas.
  • Obtener información sobre las posibles funciones no fotoquímicas de las FArhodopsinas.

Principales métodos:

  • Para obtener datos estructurales de alta resolución se empleó la criomicroscopia electrónica (Cryo-EM).
  • Se realizaron análisis bioquímicos para caracterizar la proteína y sus interacciones.

Principales resultados:

  • La estructura cryo-EM de FArhodopsin se resolvió con éxito, revelando su arquitectura molecular.
  • Los datos estructurales proporcionaron información sobre por qué la FArhodopsina no puede unirse a la retina.
  • El estudio identificó posibles sitios de interacción y características estructurales relevantes para las funciones no fotoquímicas.

Conclusiones:

  • La estructura determinada de FArhodopsin proporciona una comprensión fundamental de esta subclase de rodopsina.
  • Estos hallazgos sugieren que las FArhodopsinas pueden haber desarrollado funciones distintas independientes de la detección de luz.
  • La investigación futura puede basarse en esta información estructural para explorar las funciones no fotoquímicas específicas de las FArhodopsinas.