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Updated: Sep 8, 2025
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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
Published on: May 27, 2015
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Miocarditis auricular derecha aislada secundaria a Listeria monocytogenes
Paula Poveda Velazquez1, Mohammed Y Khanji2, Reem Laymouna1
1Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom.
JACC. Case reports
|September 5, 2025
Resumen
La miocarditis por Listeria monocytogenes es una enfermedad rara y potencialmente mortal. El diagnóstico temprano y el tratamiento con antibióticos y anticoagulantes son cruciales para la recuperación, especialmente en pacientes inmunocomprometidos.
Área de la Ciencia:
- Cardiología
- Enfermedades infecciosas
- Inmunología
Sus antecedentes:
- La miocarditis debida a Listeria monocytogenes es una afección rara pero grave.
- Los pacientes con lupus eritematoso sistémico sometidos a inmunosupresión están en riesgo.
- La participación auricular en la miocarditis es poco común.
Objetivo del estudio:
- Para reportar un caso raro de miocarditis inducida por Listeria monocytogenes con afectación auricular.
- Para resaltar la utilidad diagnóstica de las imágenes multimodales.
- Hacer hincapié en la importancia de considerar las causas infecciosas en pacientes inmunocomprometidos.
Principales métodos:
- Presentación del caso de una mujer de 54 años con dolor en el pecho y fiebre.
- El diagnóstico incluye ECG, FDG-PET y resonancia magnética cardíaca.
- Culturas de sangre para la identificación del patógeno.
- Tratamiento con antibióticos y anticoagulantes.
Principales resultados:
- Troponina y CRP elevados, anomalías en el ECG.
- FDG-PET mostró absorción auricular derecha.
- La resonancia cardíaca reveló engrosamiento del atrio derecho, akinesia, trombo y aumento tardío de gadolinio.
- Listeria monocytogenes fue identificada en cultivos de sangre.
- Tratamiento exitoso con resolución de la disfunción cardíaca y el trombo.
Conclusiones:
- Listeria monocytogenes puede causar miocarditis potencialmente mortal con afectación de las aurículas.
- Las imágenes multimodales son vitales para el diagnóstico y la orientación del tratamiento.
- Se deben descartar las etiologías infecciosas antes de iniciar o continuar la inmunosupresión.
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