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Primer Caso Informado de Enfermedad de Kimura Intracárdica
Andrew D Wisneski1, Jamal S Rana2, Eugene Fan3
1Division of Cardiothoracic Surgery, Department of Surgery, University of California San Francisco, San Francisco, California, USA.
JACC. Case reports
|September 6, 2025
Resumen
Este informe detalla el primer caso de enfermedad intracardíaca de Kimura, una rara condición inflamatoria. La resección quirúrgica de la masa cardíaca fue exitosa y no se observó recurrencia durante el seguimiento.
Área de la Ciencia:
- Cardiología
- Patología
- Enfermedades raras
Sus antecedentes:
- La enfermedad de Kimura es una condición inflamatoria rara que afecta típicamente la cabeza y el cuello con nódulos subcutáneos.
- La afectación intracardiaca de la enfermedad de Kimura es excepcionalmente rara, sin casos documentados previos.
- Este caso presenta el primer caso de la enfermedad de Kimura que se manifiesta dentro del corazón.
Objetivo del estudio:
- Para reportar el primer caso documentado de enfermedad intracardiaca de Kimura.
- Para resaltar los desafíos de diagnóstico y el manejo exitoso de esta rara presentación.
- Contribuir a la comprensión de las posibles manifestaciones extranodal de la enfermedad de Kimura.
Principales métodos:
- Una paciente de 57 años presentó síntomas cardíacos incluyendo un soplo cardíaco y disnea.
- La ecocardiografía identificó una masa significativa (3 cm) que obstruye el tracto de flujo ventricular derecho.
- Se realizó la resección quirúrgica de la masa y el subsiguiente reemplazo de la válvula pulmonar, seguido de un análisis histopatológico para el diagnóstico.
Principales resultados:
- El examen patológico confirmó la masa resecada como enfermedad de Kimura.
- El paciente se sometió a un tratamiento quirúrgico sin esteroides adyuvantes ni radioterapia.
- Un año de vigilancia activa, incluida la ecocardiografía, no mostró evidencia de recurrencia de la enfermedad.
Conclusiones:
- Este caso establece la enfermedad intracardiaca de Kimura como una entidad clínica distinta.
- La resección quirúrgica puede ser un tratamiento primario eficaz para la enfermedad intracardiaca de Kimura.
- La vigilancia a largo plazo es crucial para controlar la posible recurrencia de la enfermedad de Kimura.
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