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Updated: Jan 6, 2026

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Estructura y mecanismo del transportador de calcio mitocondrial NCLX

Minrui Fan1, Chen-Wei Tsai2,3, Jinru Zhang1

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Nature
|September 10, 2025
PubMed
Resumen

El transportador de calcio mitocondrial (Ca2+) NCLX funciona como un intercambiador de H2+, no de Na2+. Este descubrimiento, revelado por las estructuras cryo-EM, aclara los mecanismos de transporte de NCLX y la regulación mitocondrial de Ca2+.

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