Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Position of Equilibrium in Acid-Base Reactions02:05

Position of Equilibrium in Acid-Base Reactions

14.5K
In any solution, the value of pKa indicates whether an acid is completely dissociated or not. A negative pKa corresponds to a stronger acid, whereas a positive pKa corresponds to a weaker acid. Consider the reaction between ammonia and an ethoxide ion. In this reaction, ethanol with a pKa of 15.9 is a stronger acid than ammonia with a pKa of 38. Recall that the strong acid forms a weak conjugate base, and a weak acid forms a strong conjugate base. Hence, the ethoxide ion is a weak base.
14.5K
Weak Acid Solutions04:02

Weak Acid Solutions

42.2K
Few compounds act as strong acids. A far greater number of compounds behave as weak acids and only partially react with water, leaving a large majority of dissolved molecules in their original form and generating a relatively small amount of hydronium ions. Weak acids are commonly encountered in nature, being the substances partly responsible for the tangy taste of citrus fruits, the stinging sensation of insect bites, and the unpleasant smells associated with body odor. A familiar example of a...
42.2K
Calculating Equilibrium Concentrations02:05

Calculating Equilibrium Concentrations

52.6K
Being able to calculate equilibrium concentrations is essential to many areas of science and technology—for example, in the formulation and dosing of pharmaceutical products. After a drug is ingested or injected, it is typically involved in several chemical equilibria that affect its ultimate concentration in the body system of interest. Knowledge of the quantitative aspects of these equilibria is required to compute a dosage amount that will solicit the desired therapeutic effect.
A more...
52.6K
Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

11.1K
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
11.1K
Regioselectivity and Stereochemistry of Hydroboration02:36

Regioselectivity and Stereochemistry of Hydroboration

9.4K
A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn stereochemistry.
9.4K
Weak Base Solutions03:21

Weak Base Solutions

24.8K
Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
24.8K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Controlled Amine-Borane Dehydropolymerization Enabled by Mechanistic Insight Using the Ir(<sup>t</sup>Bu-POCOP)H<sub>2</sub> Catalyst.

Journal of the American Chemical Society·2026
Same author

Evidence for Transient Ylide Intermediates of the Type <sup>t</sup>Bu<sub>2</sub>P(H)=CHZ That Are Prototropic Tautomers of <sup>t</sup>Bu<sub>2</sub>PCH<sub>2</sub>Z.

Inorganic chemistry·2026
Same author

Aryl Boroxines via Rotary Evaporation.

Organic letters·2026
Same author

A Stopped-Flow Instrument for Millisecond Timescale Reaction Monitoring on a Standard NMR Spectrometer.

Magnetic resonance in chemistry : MRC·2026
Same author

Pure Gaussian Apodisation Reduces Integral Crosstalk Sensitivity in Quantitative NMR.

Magnetic resonance in chemistry : MRC·2026
Same author

Synthesis of Dideuterofluoroarene <sup>3</sup>ΔF(D)-NMR Reporter-Resolvers for Structural, Mechanistic, and Kinetic Studies.

The Journal of organic chemistry·2026

Video Experimental Relacionado

Updated: Jan 15, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

3.4K

El equilibrio de la boroxina y el ácido bórico

Chen Li1, Lia Sotorrios2, Patrick J Boaler1

  • 1University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, U.K.

Journal of the American Chemical Society
|October 13, 2025
PubMed
Resumen

El estudio revela un mecanismo de tres pasos para la interconversión boroxina-ácido borónico, identificando los intermediarios clave y el papel catalítico del agua. Esto aclara su comportamiento químico y aplicaciones.

Más Videos Relacionados

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants
08:56

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants

Published on: March 25, 2017

8.0K
Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.9K

Videos de Experimentos Relacionados

Last Updated: Jan 15, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

3.4K
Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants
08:56

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants

Published on: March 25, 2017

8.0K
Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.9K

Área de la Ciencia:

  • Química orgánica
  • Química Física
  • La cinética química

Sus antecedentes:

  • El equilibrio boroxina-ácido borónico es crucial para sus propiedades y aplicaciones.
  • El mecanismo y la cinética de esta interconversión no se comprenden bien.

Objetivo del estudio:

  • Aclarar el mecanismo detallado y la cinética de la interconversión ácido arilborónico-arilboroxina.
  • Investigar el papel de las propiedades del disolvente y el agua en la secuencia hidrolítica.

Principales métodos:

  • Espectroscopia de RMN y UV, incluidas las titulaciones y la cinética de flujo detenido.
  • Transferencia de magnetización, efectos de isótopos cinéticos, simulaciones numéricas y cálculos de DFT.
  • En los cálculos del DFT se utilizaron enfoques explícitos de la solvencia.

Principales resultados:

  • Se identificaron dos productos intermedios de anhídrido acíclico en un proceso de interconversión de tres pasos.
  • El agua actúa como reactivo y catalizador; las propiedades del aceptor de enlace de hidrógeno del disolvente influyen en el equilibrio.
  • Descubrió equilibrios competitivos y vías de transferencia asociativa directa.

Conclusiones:

  • Los hallazgos clarifican el complejo mecanismo hidrolítico de las boroxinas y los ácidos borónicos.
  • Proporciona una herramienta para estimar la especiación de equilibrio y tiene implicaciones para diversas aplicaciones.
  • Destaca la importancia de los efectos de los disolventes y las vías de reacción alternativas.