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Updated: Jan 14, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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Establecimiento de tendencias de selectividad con reacciones de tioesterasas y policetidas semisintéticos

Zachary C Litman1, Yuanhuang Chen1, David H Sherman1,2

  • 1University of Michigan, Life Sciences Institute, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|October 24, 2025
PubMed
Resumen

Este estudio investiga las tioesterasas (TE), enzimas clave en la síntesis de policetidos. Los TE mutantes muestran una actividad más amplia, ampliando el potencial para el descubrimiento de nuevos productos terapéuticos naturales.

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