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Updated: Aug 10, 2026

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
Modelado asistido por computadora de parámetros hemodinámicos en la bifurcación normal de la arteria carótida común
V P Derbilova1, R A Vinogradov1,2, Yu N Zakharov3,4
1Kuban State Medical University of Ministry of Ministry of Healthcare of the Russian Federation, 350063, Krasnodar, Russian Federation.
Background:
Computational fluid dynamics is currently widely used to study the parameters of blood flow and their alterations in pathological states and are important indicators for diagnosis of atherosclerosis.
Objective:
This study was aimed at determining risk zones for development of atherosclerosis by means of computational fluid dynamics in patients without carotid artery pathology.
Patients And Methods:
Using contrast-enhanced computed tomography, a total of 10 bifurcations of common carotid arteries were examined. The obtained findings were analyzed by means of computational fluid dynamics. The area of bifurcation was divided into segments. In each segment, we identified zones most prone to the development of atherosclerosis.
Results:
The obtained findings made it possible to draw a conclusion that in patients without pathology of carotid arteries, the zone of bifurcation is a place of potential development of atherosclerotic plaques. It was confirmed by low values of wall shear stress. Besides, our study made it possible to determine exact localization of risk zones, i. e., proximal portion of the internal carotid artery.
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