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Desarrollo de un nuevo ensayo de toxicidad in vitro para predecir la toxicidad por inhalación en ratas

Arpamas Vachiraarunwong1, Masaki Fujioka2, David B Alexander3

  • 1Department of Environmental Risk Assessment, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

Toxicology letters
|December 12, 2025
PubMed
Resumen

Un nuevo ensayo in vitro que utiliza células pulmonares humanas predice la toxicidad aguda por inhalación, reduciendo las pruebas en animales. Este ensayo A549-NRU muestra una fuerte correlación con los resultados de estudios en animales, ofreciendo una alternativa prometedora para las pruebas de toxicidad.

Palabras clave:
ensayo A549-NRUtoxicidad aguda por inhalaciónalternativa a las pruebas en animalespulverización intratraqueal intrapulmonarpredicción de toxicidad

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