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Deterioro cognitivo subjetivo en veteranos militares mayores de EE. UU.: Un estudio longitudinal representativo a
Michael F Georgescu1, Ian C Fischer2,3, May A Beydoun1
1Laboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA.
Journal of Alzheimer's disease reports
|December 15, 2025
Resumen
El deterioro cognitivo subjetivo (SCD), un riesgo temprano de demencia, afectó al 5,4% de los veteranos mayores. Los predictores clave incluyeron baja resiliencia, dolor crónico y problemas de sueño, lo que sugiere objetivos de intervención.
Área de la Ciencia:
- Gerontología
- Neurociencia
- Salud Pública
Sus antecedentes:
- El deterioro cognitivo subjetivo (SCD) es un indicador temprano reconocido de demencia.
- Comprender la incidencia y los predictores del SCD es crucial para las estrategias de intervención temprana.
Objetivo del estudio:
- Determinar la incidencia de SCD clínicamente significativo en 3 años en veteranos militares de EE. UU. de 60 años o más.
- Identificar los predictores clave de SCD en este grupo demográfico.
Principales métodos:
- Se utilizó la Escala de Función Cognitiva-Revisada del Medical Outcomes Study.
- Se analizaron datos de una muestra nacional de 1858 veteranos militares de EE. UU. de ≥60 años.
- Se evaluó la incidencia y los predictores de SCD en 3 años.
Principales resultados:
- El SCD clínicamente significativo ocurrió en el 5,4% de los veteranos durante 3 años.
- La disminución cognitiva promedio fue de 1,73 desviaciones estándar.
- Los predictores más fuertes identificados: menor resiliencia (específicamente "Me recupero después de una dificultad" y "Superar el estrés puede hacerme más fuerte"), dolor crónico y dificultades para dormir.
Conclusiones:
- La menor resiliencia, el dolor crónico y las dificultades para dormir son predictores significativos de SCD en veteranos mayores.
- Las intervenciones dirigidas a la resiliencia, el manejo del dolor y la higiene del sueño pueden ayudar a mitigar el SCD.
- Los hallazgos resaltan vías potenciales para prevenir la progresión de la demencia en poblaciones de veteranos.
Palabras clave:
enfermedad de Alzheimerepidemiologíaestudios longitudinalesdeterioro cognitivo subjetivoMás Videos Relacionados
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