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Updated: Jan 8, 2026

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Dirigirse a las variantes germinales de RUNX1: Agentes en investigación

Saman Ghalamkari^1,2, Christopher N Hahn^1,3,2, Amelia Lau^1,2

¹Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, SA, Australia.

Current hematologic malignancy reports

|December 15, 2025

Resumen

Están surgiendo nuevas terapias para el Trastorno Plaquetario Familiar con Neoplasia Mieloide (FPDMM), centrándose en la corrección de variantes genéticas de RUNX1 y en la modulación de vías inflamatorias para prevenir neoplasias hematológicas.

Palabras clave:

Trastorno Plaquetario Familiar Terapia génica Línea germinal RUNX1 Terapias dirigidas Factor de transcripción

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